Steady electrodiffusion in hydrogel-colloid composites: macroscale properties from microscale electrokinetics

Steady electrodiffusion in hydrogel-colloid composites: macroscale properties from microscale electrokinetics.

A rigorous microscale electrokinetic model for hydrogel-colloid composites is adopted to compute macroscale profiles of electrolyte concentration, electrostatic potential, and hydrostatic pressure across membranes that separate electrolytes with different concentrations. The membranes are uncharged polymeric hydrogels in which charged spherical colloidal particles are immobilized and randomly d...

Simulating macroscale brain circuits with microscale resolution

Design of stiff, tough and stretchy hydrogel composites via nanoscale hybrid crosslinking and macroscale fiber reinforcement.

Hydrogels' applications are usually limited by their weak mechanical properties. Despite recent great progress in developing tough hydrogels, it is still challenging to achieve high values of , toughness and modulus all together in synthetic hydrogels. In this paper, we designed highly stretchable, tough, yet stiff hydrogel composites via a combination of nanoscale hybrid crosslinking and macro...

Resolving macroscale and microscale heterogeneity in virus filtration

In this paper, we characterize the filtration and deposition profiles of a recombinant analog of Norwalk virus, an important waterborne pathogen, in packed beds of saturated quartz sand under both ‘clean-bed’ and ‘dirty-bed’ conditions. Under clean-bed conditions with NaCl as the electrolyte, the retained Norwalk virus particles decline like a power-law with depth. The power-law decay in retain...

A Spotlight on Bridging Microscale and Macroscale Human Brain Architecture

We place a spotlight on the emerging trend of jointly studying the micro- and macroscale organization of nervous systems. We discuss the pioneering studies of Ding et al. (2016) and Glasser et al. (2016) in the context of growing efforts to combine and integrate multiple features of brain organization into a multi-modal and multi-scale examination of the human brain.